Effects of glucose oxidase and bile acid on laying performance,egg quality,antioxidant function,immune function,and liver health of laying hens
LI Haifeng
CHEN Shijie
CAO Zhengyu
LIU Chang
CHEN Cheng
ZHAO Jie
Abstract：The experiment aimed to investigate the effects of glucose oxidase(GOD)and bile acid(BA)on the laying performance,egg quality,antioxidant function,immune function,and liver health in Jingfen No.6 laying hens.A total of 4 800 healthy 40-week-old laying hens were randomly divided into four groups,with six replicates per group and 200 hens per replicate.The control group was fed a basal diet,while the GOD group,BA group,and GB group were supplemented with 50 mg/kg GOD,250 mg/kg BA,and 50 mg/kg GOD+250 mg/kg BA,respectively,based on the basal diet.The trial period was one week and the formal test period was six weeks.The results showed that the feed-to-egg ratio in the GB and BA groups was significantly lower than that in the control group(P＜0.05).The GB group exhibited significantly higher average egg weight and egg shape index compared to the control group(P＜0.05),but significantly lower eggshell strength(P＜0.05).The yolk color scores in the other groups were significantly lower than in the GB group(P＜0.05).Malondialdehyde content in the BA and GB groups was significantly higher than in the control group(P＜0.05),while glutathione peroxidase activity in the GB group was significantly higher than in the other groups(P＜0.05).The immunoglobulin G content in the control group was significantly lower than in the other groups(P＜0.05),whereas immunoglobulin A and immunoglobulin M concentrations in the GB group were significantly higher than in the control group(P＜0.05).The histological structure of liver structure in the GB group was normal without pathological histological changes.Research shows that dietary supplementation with glucose oxidase and bile acid can reduce the feed-to-egg ratio,improve egg quality,enhance antioxidant and immune functions,and maintain liver health in laying hens.
Keywords：glucose oxidasebile acidantioxidant functionimmune functionliver healthlaying henslaying performance
Publication Date：2025-06-16
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 26-30 )