Effects of glucose oxidase on growth performance,immunity,and antioxidant function of yellow feather broilers

SUN Liuxia; WU Bobo; YUAN Wenju; LI Jia; ZHAO Qingfeng

doi:10.13557/j.cnki.issn1002-2813.2025.10.008

Abstract：The experiment aimed to investigate the effects of glucose oxidase on the growth performance,immunity,and antioxidant function of yellow feather broilers.A total of 1 000 healthy one-day-old yellow feather broilers were randomly divided into four groups,with five replicates per group and 50 broilers per replicate.The control group was fed a corn-soybean meal-based diet,while the GOD 200,GOD 400,and GOD 800 groups were supplemented with 200,400,and 800 mg/kg of glucose oxidase on the basis of the basic diet,respectively.The test period was 42 days.The results showed that from 22 to 42 days of age and from 1 to 42 days of age,compared to the control group,the average daily weight gain,body weight at 42 days of age,and spleen index at 21 days of age of the GOD 400 group were significantly increased(P<0.05),and the feed-to-weight ratio was significantly reduced(P<0.05).Compared to the control group,the serum immunoglobulin G(IgG)level of the GOD 400 group was significantly elevated(P<0.05),while the levels of interleukin-6(IL-6)and interleukin-1β(IL-1β)in the serum of all experimental groups were significantly decreased(P<0.05).The levels of interleukin-10(IL-10)in the serum of the GOD 400 and GOD 800 groups were significantly increased(P<0.05),and the levels of tumor necrosis factor-α(TNF-α)in the serum of the GOD 200 and GOD 400 groups were significantly decreased(P<0.05).Compared to the control group,the content of malondialdehyde(MDA)in the serum of the GOD 400 group was significantly reduced(P<0.05),and the activity of glutathione peroxidase(GSH-Px)in the serum of the GOD 200 and GOD 400 groups was significantly increased(P<0.05).The activity of superoxide dismutase(SOD)in the serum of all experimental groups was significantly increased(P<0.05).The study indicates that 400 mg/kg of glucose oxidase has the best effects on the growth performance,immune function,and antioxidant function of yellow feather broilers.