Effects of antimicrobial peptide on growth performance,nutrient apparent digestibility,and stress tolerance of weaned meat rabbits
DIAO Hui
ZHANG Jing
TANG Wenjie
YAN Jiayou
ZHOU Mengjia
HUANG Chongbo
LI Shuwei
ZHANG Jie
Abstract：The experiment aimed to investigate the effects of antimicrobial peptide on the growth performance,nutrient apparent digestibility,and stress tolerance of weaned meat rabbits.A total of 198 weaned Ira meat rabbits with an average weight of(0.979±0.023)kg at the age of 35 days were selected.The random block design method was used to randomly divide them into two groups,with 11 replicates per group and nine weaned meat rabbits per replicate.The control group was fed a basic diet,while the antimicrobial peptide group was fed the basic diet supplemented with 500 mg/kg of antimicrobial peptide.The pre-test period was seven days and the formal test period was 30 days.The results showed that compared with the control group,the body weight on day 30 and the average daily gain(ADG)of the whole period of weaned meat rabbits in the antimicrobial peptide group were significantly increased(P＜0.05),and the ratio of feed to gain(F/G)from day 1 to 15 and the whole period was significantly decreased(P＜0.05).Compared with the control group,the antimicrobial peptide group significantly improved the apparent digestibility of crude fiber,the content of heat shock protein 70(HSP70),immunoglobulin G(IgG),interleukin-10(IL-10),interferon-γ(INF-γ)in serum,and the activity of lysozyme(LZM)and superoxide dismutase(SOD)(P＜0.05),while significantly reducing the content of malondialdehyde(MDA)and cortisol(COR),and the potassium-sodium ratio(K/Na)(P＜0.05).The study indicates that 500 mg/kg antimicrobial peptide can improve the nutrient apparent digestibility,enhance immune function,improve antioxidant and anti-stress ability of meat rabbits,and effectively promote their growth.
Keywords：antimicrobial peptidenutrient apparent digestibilityimmunityantioxidant capacitystress toleranceweaned meat rabbits
Publication Date：2025-02-16
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 74-78 )