Current status and treatment progress of psychiatric drug-induced leukopenia
Zhai Qian
Yan Fang
Abstract：White blood cells,especially neutrophils,are crucial for defending against infections caused by important pathogens such as bacteria and fungi.When it is significantly reduced,life-threatening complications may occur.In clinical practice,leukopenia/neutropenia caused by non-chemotherapy drugs is often asymptomatic in its early stages,making it difficult to detect promptly and potentially leading to serious complications.Nearly all major categories of psychiatric drugs are associated with leukopenia/neutropenia,which may occur at any time during treatment,and the risk is difficult to predict.Therefore,enhancing awareness of psychiatric drug-induced leukopenia/neutropenia is particularly important for psychiatrists.This article provides a review of the incidence,clinical characteristics,mechanisms,and conventional treatment methods for leukopenia/neutropenia induced by commonly psychiatric drugs.
Keywords：Antipsychotic agentsAntidepressive agentsLeukopeniaNeutropeniaReview
Publication Date：2026-03-20
Online Publishing Date：2026-03-31(First online date of this platform, not the publication date of the document)
Pages：8( 221-228 )