Value of metagenomic next-generation sequencing in neurosurgical patients with acquired infectious diseases
Liu Ziwei
Li Xinmeng
Liu Weiyu
Liao Zhiyi
Zhao Chunmei
Huang Xianjian
Abstract：Neurosurgical patients are prone to acquired infectious diseases due to a variety of factors such as indwelling catheters,long-term bedridden,and low resistance,leading to a poor prognosis.Traditional pathogen detection methods take a long time to detect pathogens and have a low positive rate,making it easy to delay treatment.As a method of detecting pathogens,metagenomic next-generation sequencing(mNGS)is characterized by fast detection speed and high sensitivity,which can effectively detect pathogens and provide clinicians with a basis for antibiotic use.This paper analyzes the effectiveness of mNGS in the diagnosis and treatment of acquired infectious diseases in neurosurgical patients,with a view to providing a reference for the future treatment of acquired infectious diseases in neurosurgical patients.
Keywords：Intracranial infectionPulmonary infectionBloodstream infectionUrinary tract infectionsNext-generation sequencingNeurosurgery departmentMicrobial cultureReview
Publication Date：2025-09-20
Online Publishing Date：2025-09-23(First online date of this platform, not the publication date of the document)
Pages：6( 674-679 )