Research progress on the pathogenesis of metabolism associated fatty liver disease combined with depressive disorder
Liu Pule
Si Xiaying
Dong Qiangli
Abstract：Numerous studies have shown that metabolism associated fatty liver disease and depressive disorders often occur together.In order to delve deeper into the relationship between the two and their intertwined pathophysiological mechanisms,this article reviews recent studies on the pathogenesis of the two,covering neurotransmitter imbalance,systemic inflammation,insulin resistance,gut microbiota dysbiosis,structural changes in the brain,endocrine disrupters,and dietary habits,with the aim of analyzing these potential mechanistic links and looking ahead to the future research direction.
Keywords：Depressive disorderMetabolic associated fatty liver diseaseEtiologyReview
Publication Date：2025-08-20
Online Publishing Date：2025-08-25(First online date of this platform, not the publication date of the document)
Pages：6( 598-603 )