Efficacy and biological mechanism of repetitive transcranial magnetic stimulation in the treatment of gait disorder in Parkinson disease
Niu Xiaohui
Yin Wenchao
Wang Cui
Abstract：Parkinson disease(PD)is the second most common neurodegenerative disease that occurs in old people,and including motor and non-motor symptoms,in which gait disorder severely affect the quality of life of PD patients in terms of independence.At present,levodopa medication remain the primary method for treating the symptoms of PD,but the improvement of gait disorders still very limited.Repetitive transcranial magnetic stimulation(rTMS)is a very promising non-invasive neuromodulation technology,which has certain efficacy in improving gait disorder.Therefore,this paper reviews the therapeutic plan,therapeutic target,therapeutic frequency,and mechanism of action of rTMS in improving gait disorder of PD.In order to provide theoretical basis and evidence for the use of rTMS in the treatment of PD gait disorder.
Keywords：Repetitive transcranial magnetic stimulationParkinson diseaseGait disorderTherapeutic effectMechanismReview
Publication Date：2025-05-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 325-331 )