Research progress on the correlation between NOS1AP and schizophrenia
Han Yushuo
Tang Funian
Li Keqing
Zhang Yunshu
Zhang Lili
Abstract：Schizophrenia is a chronic and severe mental disorder with unknown etiology.The etiology of schizophrenia has always been a key research direction in psychiatry.Nitric oxide synthase 1 adaptor protein(NOS1AP)is an adaptor protein that regulates neuronal function through the N-methyl-D-aspartate-receptor NMDAR/neuronal nitric oxide synthase(nNOS)pathway.In recent years,more and more evidence has shown that NOS1AP plays a certain role in the occurrence and development of schizophrenia.This article reviews the correlation between NOS1AP and schizophrenia,as well as its mechanism in schizophrenia,in order to further explore the role of NOS1AP in the occurrence and development of schizophrenia and provide ideas for the treatment of schizophrenia patients.
Keywords：SchizophreniaNOS1APNeuronal nitric oxide synthaseReview
Publication Date：2025-02-19
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 109-115 )