New progress in the research of resting state brain functional connectivity in early-onset schizophrenia
Shen Qingqing
Xia Lei
Hao Mingru
Liu Huanzhong
Abstract：In recent years,it has been considered that schizophrenia is a disorder of brain functional connectivity.The functional connectivity refers to the statistical temporal correlation of low-frequency fluctuations between different regions of the brain.As a serious mental disease,early-onset schizophrenia also has changes in brain function connection.However,the relationship between early-onset schizophrenia and brain function connection is still not clear,making it a hot research topic in recent years.The resting state of brain function reflects the pattern of brain activity in a resting state.With the continuous advancement of brain functional connectivity analysis methods,the functional connectivity of resting brain network provides important technical support for understanding and identifying schizophrenia,establishing diagnostic models of schizophrenia,and improving the prognosis of patients.This article aims to review the changes in resting-state brain network functional connectivity and brain functional connectivity in early-onset schizophrenia,as well as the correlation between brain functional connectivity and core symptoms in early-onset schizophrenia,in order to provide ideas and references for understanding the physiological mechanism of early-onset schizophrenia and exploring therapeutic targets.
Keywords：Resting stateBrain functional connectivityEarly-onset schizophreniaCore symptomsReview
Publication Date：2025-02-19
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 77-82 )