Prediction of recurrence risk after the first episode of SeLECTS using high-frequency scalp EEG oscillations
Che Yuanyuan
Huang Zhixin
Chen Hui
Zha Jian
Zhong Jianmin
Chen Yong
Abstract：Objective To explore the significance of high-frequency oscillations(HFOs)in scalp electroencephalography in predicting the risk of recurrence of self-limited epilepsy with centro-temporal spikes(SeLECTS)with central temporal spikes after the first seizure.Methods A retrospective study was conducted on 114 children with first onset SeLECTS who were admitted or treated in the outpatient department of Jiangxi Children's Hospital from June 2019 to June 2022.Their scalp EEG HFOs were measured and followed up for 6 months.According to whether epilepsy recurs or not,they were divided into a recurrent group and a non-recurrent group,and the detection rate of HFOs in the two groups of children was compared.Results Among 114 children with SeELECTS,42 cases(36.84%)experienced recurrent epilepsy within 6 months of their first seizure.At the initial diagnosis,HFOs were recorded in 7 cases(9.72%)of the non-recurrence group and 13 cases(30.95%)of the recurrence group on the EEG.The difference between the two was statistically significant(χ2=6.786,P＜0.05).Six months later,the EEG was re-examined,HFOs were recorded in 5 cases(6.94%)of the non-recurrence group and 11 cases(26.19%)of the recurrence group.The difference between the two groups was also statistically significant(χ2=8.144,P＜0.05).Conclusions The detection of HFOs in scalp electroencephalography of children with SeLECTS can to some extent indicate an increased and relatively stable risk of recurrence of the first seizure.
Keywords：EpilepsyElectroencephalogramHigh-frequency oscillationsBenign childhood epilepsy with centro-temporal spikes
Publication Date：2024-10-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 735-739 )