Discussion on the mechanism of interleukin-6 involvement in the pathogenesis of post-stroke depression
Hu Zhilin
Ge Zhaoming
Abstract：Post-stroke depression(PSD)is one of the common complications of stroke,but its pathophysiological mechanism has not been fully elucidated.In recent years,it has become a research hotspot to find serological markers related to PSD and the targets of new antidepressants.Interleukin-6(IL-6)has a wide range of biological functions and a clear pro-inflammatory effect in vivo,which is closely related to the occurrence of PSD.This article aims to review the relationship between IL-6 and the pathogenesis of PSD,and to explore the possibility of IL-6 as a potential therapeutic target.
Keywords：Interleukin-6StrokePost-stroke depressionMechanism of actionReview
Publication Date：2024-08-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 533-538 )