Relationship between neuroticism, depression and cognitive function in patients with first-episode depression
Liu Penghong
Li Yening
Tian Yu
Song Xiaoyue
Zhang Kerang
Abstract：Objectives? To explore the relationship between neuroticism, depression and cognitive function in patients with first-episode depression. Methods? The 17-item Hamilton Depression Scale (HAMD-17), Eysenck Personality Questionnaire (EPQ), Wechsler Adult Intelligence Test (WAIS-RC) were used to evaluate and study 156 cases of patients with first-episode depression. Results?(1) In depressive patients, the neurotic personality was positively correlated with the total score of HAMD-17 (r=0.301,P＜ 0.01) but was negatively correlated with Verbal IQ (VIQ) (r=-0.276, P＜0.01), Performance IQ (PIQ) (r=-0.330,P＜0.01) and Full IQ (FIQ) (r=-0.376,P＜ 0.01). (2) Depressive symptoms played a partial mediating role between neurotic personality and WAIS-IQ, the mediator effect was 38.7%. Conclusions? Neurotic personality of first-episode depression patients affected cognitive function through depressive symptoms.
Keywords：DepressionNeuroticismCognitive function
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 333-336 )