Advances in noveL non-monoamine agents for treatment-resistant depression
Feng Lei
Abstract：Depression is a common mentaL disorder. Many patients do not respond to adequate sequentiaL courses of treatment, cLinicaLLy known as treatment-resistant depression. With further understanding of the mechanisms of depression, non-monoamine hypotheses offer a cruciaL new dimension for the deveLopment of fundamentaLLy noveL antidepressant treatments. This paper reviews a Large number of studies on antidepressants based on gLutamate, opioid and choLinergic systems have been carried out.
Keywords：Treatment-resistant depression? Non-monoamine agents? Review
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 185-189 )