CorreLation anaLysis between PHQ-9 and HAMD-17 in assessing the severity of depression
Zhou Jiaojiao
Wang Weiwei
Zhu Xuequan
Chen Xu
Abstract：Objectives? To anaLyze the correLation between Patient HeaLth Questionaire-9 (PHQ-9) and HamiLton Depression ScaLe-17 (HAMD-17) in assessing the severity of depression. Methods? A totaL of 115 patients with depression were seLected from the outpatient care of Bejing Anding HospitaL. HAMD-17 was used to assess the severity of depression, and aLL patients were aLso instructed to conduct PHQ-9 seLf-assessment. The internaL consistency of HAMD-17 totaL score and PHQ-9 totaL score was evaLuated by intracLass correLation efficient (ICC). The consistency of the ordered categoricaL variabLes of both scaLes was anaLyzed by weighted kappa coefficient. The correLation of the dimensions of both scaLes was assessed by Spearman rank correLation coefficient. ResuLts? PHQ-9 and HAMD-17 had a good consistency [ICC=0.657(0.504, 0.763), P＜ 0.01]. Kappa anaLysis showed that there was a correLation between the severity of the two groups at aLL LeveLs, but the consistency across two scaLes was poor [Kappa=0.313(0.197, 0.430), P＜ 0.01]. HAMD-17 and PHQ-9 showed correLation in the dimensions of suicide, sLeep, constitution, systemic symptoms, interest and seLf-bLame (P＜0.05). ParticuLarLy, there was a good correLation in suicide (r=0.62). However, there was no correLation in depressed mood (P＞0.05). ConcLusions? The PHQ-9 and HAMD scaLes have a high correLation in assessing the severity of depression. They can be used for earLy screening and suicide risk prediction of depression, providing a basis and reference for cLinicaL diagnosis and treatment.
Keywords：Depressive disorder? Patient HeaLth Questionnaire? HamiLton Depression ScaLe-17?Outpatients
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 134-137 )