Value of differential diagnosis of the combination of eye movement and body sway examination on Parkinson disease and progressive supranuclear paralysis
Sun Zhuo
Zhong Wen
Zhou Yinping
Wang Han
Chen Xia
Abstract：Objective? To compare the characteristics of eye movement and body sway of patients with Parkinson disease (PD) and progressive supranuclear palsy (PSP). Methods? A cross-sectional study was conducted in a sequential group of patients with PD and PSP. The patients were tested for the horizontal movement of the eyeball and the somatic swinging. Collect the results, and compare the differences between PD group, PSP group, and that of the health group. Results? PD group consisted of 18 PD patients [male: 11, age: 67 (60, 71) years dd]. PSP group consisted of 9 patients with PSP [male: 7, age: 74 (66, 78.5)years old]. Healthy group consists of 44 healthy people [male: 15, age: 67.5 (62, 71)years old]. The results of hierarchical regression analysis showed that the difference of eye movement index and somatic swinging index between healthy people and PD patients was statistically significant (P＜ 0.01) after controlling the potential effects of age and sex. The difference of eye movement index between healthy people and PSP patients was statistically significant (P＜0.01). There was no significant difference of the body swinging index between healthy people and PSP patients (P＞ 0.05). There was no statistical significance of either eye movement index or body swinging index between the PD patients and the PSP patients (P＞0.05). Conclusions? The combination of eye movement and body sway examinations might be helpful to identify PSP from PD.
Keywords：Parkinsonism? Parkinson disease? Progressive supranuclear palsy? Eye movementBody sway
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 21-24 )