Relationship between affective temperament and bipolarity in depression episode

doi:10.3969/j.issn.1009-6574.2015.04.018

Abstract：Objective To explore the relationship between affective temperament and bipolarity in depression episode .Methods This study was a cross-sectional study .Thirty -six unipolar depression patients treated 12 weeks were included ,the medication compliance and the clinical cure rate were col‐lected .The unipolar depression with exuberant and cycle temperament was classified as soft bipolar spec‐trum according with the soft bipolar spectrum theory and the temperament evaluation scale . Results There were 10(27 .8% ) soft bipolar spectrum patients (9 patients were clinically cured) and 26 rigorous unipolar depression(18 patients were clinically cured) .Patients with bipolar spectrum were sig‐nificantly younger than patients with unipolar depression .There were significantly different between bi‐polar spectrum with unipolar depression in affective temperament(i .e .cycle ,anxiety ,irritability and de‐pression temperament) (P < 0 .01) .Bipolar spectrum patients with lithium treatment and had signifi‐cantly higher remission rates than patients without lithium treatment (P< 0 .01) .Conclusions The af‐fective temperament may predict the bipolarity in depression episode ,mood stabilizers can improve clini‐cal symptoms in patients with soft bipolar spectrum ,which provide supporting evidence for the concept of soft bipolar spectrum .