Progress in Targeted Therapy and Targeted Protein Degradation for Esophageal Cancer
WANG Feifan
ZHANG Xiusen
SHI Linlin
GAO Shegan
Abstract：Surgical resection is the preferred treatment for esophageal cancer.However,due to the lack of obvious symptoms in the early stages,most patients are not eligible for surgery when they visit the doctor.Therefore,comprehensive therapies such as chemoradiotherapy,targeted therapy,and immunotherapy are crucial for controlling advanced esophageal cancer.Targeted therapy has significantly improved efficacy and reduced adverse reactions by identifying genetic variations or epigenetic characteristics of tumor cells.This review integrates the current main targeted treatment strategies for esophageal cancer and explores other emerging targets and technical methods,aiming to provide references for the development of novel targeted treatment strategies for esophageal cancer.
Keywords：esophageal cancertargeted therapytargeted protein degradation technologyproteolysis targeting chimeras
Publication Date：2026-03-25
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：5( 61-65 )