Advances in Neoadjuvant Immunotherapy for Locally Advanced Resectable Esophageal Cancer
QIAO Zhi
ZHANG Jinfeng
YANG Yingnan
WANG Xiaoyuan
LING Xiaodong
MA Jianqun
Abstract：Surgical resection is currently the preferred method for treating locally advanced resectable esophageal cancer.However,the high recurrence rate associated with surgery alone poses a significant threat to the long-term survival of patients,making a multimodal treatment strategy centered around surgery the preferred choice for esophageal cancer treatment.within this comprehensive treatment framework,neoadjuvant immunotherapy has shown significant advantages in improving patient survival rates compared to traditional neoadjuvant therapies,without a significant increase in the risk of adverse reactions.These advantages suggest that neoadjuvant immunotherapy has great potential for application in the treatment of esophageal cancer.This article aims to provide a systematic review of the current application of neoadjuvant immunotherapy in the clinical treatment of esophageal cancer.
Keywords：esophageal cancerimmune inhibitorsneoadjuvant immunotherapyimmune checkpoint
Publication Date：2025-06-25
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：9( 148-156 )