Research Progress of Tumor Microenvironment in Esophageal Cancer
ZHANG Jia-hao
HE Ke-yao
LI Chao-wei
ZHANG Zhe-yuan
DAI Ning-tao
YANG Hai-jun
LI Jun-kuo
LIU Yi-wen
SUN Wei
GUO Yi-bo
KONG Jin-yu
ZHOU Fu-you
Abstract：Esophageal cancer(EC)is a common malignant tumor of the digestive system with an insidi-ous onset and strong invasion.Additionally,most patients have a poor therapeutic effect.The tumor microen-vironment(TME)is the local environment in which tumor cells survive.It is involved in important biological processes such as tumor cell proliferation,metastasis,and immune escape.TME can regulate the occurrence and development of EC and treat drug resistance through synergistic action with tumor cells and their cyto-kines.In this paper,the composition of the EC microenvironment and the latest progress of targeted TME therapy for EC were reviewed,aiming to provide new ideas and a theoretical basis for the prevention and treat-ment of EC.
Keywords：tumor microenvironmentesophageal cancertargeted therapy
Publication Date：2023-12-30
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：7( 285-291 )