Diagnosis and treatment of recurrent giant endometrial polyp:a case report
PU Xiyue
YANG Hui
LIU Yan
QIN Juan
Abstract：Objective To investigate the clinical characteristics,key diagnostic points,therapeutic strategies,and postoperative management of recurrent giant endometrial polyps,and to improve clinical awareness of this rare condition.Methods We retrospectively analyzed the clinical data of one patient with recurrent giant endometrial polyp,including medical history,imaging findings,laboratory examination results,surgical approach,pathological characteristics,and postoperative follow-up.We also reviewed the relevant literature.Results We encountered a 27-year-old female patient with a history of multiple endometrial polyp recurrences who presented with pelvic mass and irregular vaginal bleeding.Ul-trasonography and pelvic magnetic resonance imaging(MRI)revealed a huge intrauterine space-occupying lesion,with im-aging manifestations similar to gestational trophoblastic disease.Preoperative serum human chorionic gonadotropin(hCG)was mildly elevated and carbohydrate antigen 125(CA125)was significantly increased.Exploratory laparotomy confirmed the lesion origin,and postoperative pathological examination verified the diagnosis of giant endometrial polyp.After sur-gery,the patient received hormonal regulation therapy combined with gonadotropin-releasing hormone agonist(GnRHa)pretreatment,followed by placement of a levonorgestrel-releasing intrauterine system(LNG-IUS)for long-term manage-ment.We observed no obvious recurrence during follow-up.Conclusions Recurrent giant endometrial polyps are clini-cally rare entities with complex imaging manifestations,which can easily be confused with gestational trophoblastic disease and endometrial malignant lesions.Accurate diagnosis requires comprehensive judgment based on medical history,labora-tory examination,imaging studies,and pathological results.Considering the risks of recurrence and potential malignant transformation,clinicians should establish individualized long-term follow-up and management strategies on the basis of standardized treatment.
Keywords：endometrial polypgiant endometrial polyprecurrencedifferential diagnosisindividualized treatment
Publication Date：2026-02-25
Online Publishing Date：2026-03-19(First online date of this platform, not the publication date of the document)
Pages：5( 105-108,113 )