Types of 3D bioprinting technologies and their application in modeling gastrointestinal tumors
LIU Panpan
ZHANG Yupeng
HE Chao
CUI Jianli
ZHENG Xiao
Abstract：Gastrointestinal tumors represent one of the most common malignant tumors worldwide,with their develop-ment,progression,and pesticide tolerance closely associated with alterations in the tumor microenvironment.Currently,conventional cell and animal models are unable to accurately capture the complexity and heterogeneity of tumors.Three-di-mensional(3D)bioprinting technology,an emerging biomanufacturing technology,holds significant potential for investi-gating tumorigenesis mechanisms.There are four main types of 3D bioprinting technology:inkjet bioprinting,extrusion bioprinting,laser-assisted bioprinting,and photo-curing bioprinting.This technology enables the construction of models for gastric cancer,colorectal cancer,and colorectal cancer liver metastasis through various approaches.It is widely ap-plied in simulating the tumor microenvironment,drug screening,personalized treatment,and studies on tumor metastasis mechanisms.
Keywords：three-dimensional bioprintingstomach neoplasmsgastric carcinomacolorectal carcinomatumor microenvironment
Publication Date：2025-12-25
Online Publishing Date：2026-01-12(First online date of this platform, not the publication date of the document)
Pages：5( 144-148 )