Effect of humidification via nebulization combined with preemptive analgesia on postoperative recovery in laparoscopic patients
LI Mingcheng
WANG Qiuyun
GU Huiyun
Hamila Shayimubieke
Yilixiati Yimingjiang
SUN Zhengwei
SHAN Fang
CAO Xinghua
Abstract：Objective To investigate the impact of humidification via nebulization combined with preemptive analge-sia on postoperative recovery of laparoscopic patients.Methods Eighty patients who underwent laparoscopic surgery un-der general anesthesia were prospectively selected and were divided into the observation group of 39 cases and control group of 41 cases.Both groups received intravenous drip of flurbiprofen axetil(1.0 mg/kg)and esketamine(0.5 mg/kg)before anesthesia induction as preemptive analgesia.After surgery,once patients were fully awake,the observation group received humidification via nebulization with warm water,while the control group consumed the same volume of warm wa-ter in small amounts over multiple intakes.Pain and sedation levels were assessed at 5 min after extubation and 24 h post-operatively using the visual analogue scale(VAS)and the sedation agitation scale(SAS).The recovery time of gastrointes-tinal function,adverse events,and hospital stay were recorded.The QoR-40 scale was used to evaluate recovery outcomes at 48 h postoperatively,and the Likert scale was used to assess overall patient satisfaction.Results There were no signif-icant differences in VAS or SAS scores between the two groups at 5 min after extubation and 24 h postoperatively(both P>0.05).Compared with the control group,the observation group had shorter postoperative bowel sound recovery time,first flatus time,hospital stay and less episodes of coughing and choking(all P<0.05),and showed improved QoR-40 scores and higher overall satisfaction at 48 h after surgery(all P<0.05);while nausea and vomiting rates were comparable(both P>0.05).Conclusions Humidification via nebulization combined with preemptive analgesia on postoperative recovery of laparoscopic patients can promote postoperative recovery and improve patient satisfaction by shortening the hospital stay and reducing the episodes of coughing and choking.
Keywords：enhanced recovery after surgeryhumidification via nebulizationpreemptive analgesialaparoscopic surgery
Publication Date：2025-12-25
Online Publishing Date：2026-01-12(First online date of this platform, not the publication date of the document)
Pages：5( 112-116 )