Changes of left atrial structure and function in patients with paroxysmal atrial fibrillation after pulsed field ablation based on cardiac magnetic resonance
LI Qingjie
DU Guoxiang
LIU Hao
ZHANG Tang
HUANG Huanjie
Abstract：Objective To observe the changes of left atrial structure and function in patients with paroxysmal atrial fibrillation(AF)after pulsed field ablation(PFA)based on cardiac magnetic resonance(CMR).Methods Fourteen pa-tients with paroxysmal AF scheduled for PFA were enrolled.CMR was performed at three time points:0-3 days before PFA(pre-operation),0-3 days after PFA(early post-operation),and 12 months after PFA(long-term post-operation).The measured parameters included:maximum/minimum left atrial anteroposterior diameter(LAAD-max/min),maximum/minimum left atrial transverse diameter(LATD-max/min),maximum/minimum left atrial volume(LAV-max/min),pul-monary vein ostium diameter(PVOD),left atrial anteroposterior motion amplitude(LAAP-MA),left atrial transverse mo-tion amplitude(LATR-MA),and left atrial ejection fraction(LAEF).Results All 14 patients achieved bilateral pulmo-nary vein isolation during PFA without adverse events.There were no significant differences in left atrial structural or func-tional parameters between the preoperative and early postoperative assessments(all P>0.05).At long-term post-opera-tion,LAAD-min increased,LAAP-MA decreased,and LAV-max increased in comparison with those pre-operation(all P<0.05).Conclusions PFA is effective for paroxysmal AF.No significant changes in left atrial structure or function are observed in the early post-operative period,while during the long-term follow-up,the main structural change in the left atri-um is an increase in maximum volume.
Keywords：atrial fibrillationparoxysmal atrial fibrillationpulsed field ablationatrial structureatrial func-tioncardiac magnetic resonance
Publication Date：2025-09-25
Online Publishing Date：2025-10-22(First online date of this platform, not the publication date of the document)
Pages：5( 1-5 )