Influencing factors for refeeding syndrome in critically ill patients after nutritional support
HAN Fengze
LI Xiaoli
YU Xinyue
ZHAO Xuanyu
JIA Zifei
ZHANG Xiaoli
Abstract：Objective To investigate the risk factors for refeeding syndrome(RFS)in critically ill patients following nutritional support.Methods A total of 141 critically ill patients admitted to the ICU were selected,and we observed the occurrence of RFS after nutritional support.We collected the relevant data on RFS,including general characteristics,basic conditions,laboratory test results,disease severity scoring system,and nutrition-related indicators.Univariate anal-ysis and multivariate Logistic regression were used to identify influencing factors.Results Among 141 critically ill pa-tients,66 cases developed RFS after nutritional support,and 75 cases did not develop RFS(non-RFS).Univariate analy-sis showed statistically significant differences in age,gender,tumor history,infection status,serum phosphorus,albu-min,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)score,and the nutrition risk in critically ill(NU-TRIC)score between these two groups(all P<0.05).Multivariate Logistic regression analysis identified male(OR=3.37,95%CI:1.19-9.59),infection(OR=3.87,95%CI:1.22-12.33),tumor history(OR=5.70,95%CI:1.33-24.54),the low albumin level(OR=0.89,95%CI:0.84-0.95),the low serum phosphate level(OR=0.10,95%CI:0.01-0.67),and high NUTRIC score on admission(OR=2.27,95%CI:1.50-3.42)as independent risk factors for RFS.Conclusion Gender,infection,tumor history,APTT,serum phosphate,albumin,and NUTRIC score are influencing factors for RFS in critically ill patients after nutritional support.
Keywords：critical illnessrefeeding syndromenutritional supportrisk factors
Publication Date：2025-05-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 47-51 )