Incidence and risk factors of cardiac anomalies in children with congenital scoliosis
YANG Yanrui
ZHANG Li
WANG Yingsong
ZHAO Zhi
QIAN Genghao
LI Tao
SHI Zhiyue
SONG Zhibo
Abstract：Objective To observe the occurrence of cardiac anomalies in children with congenital scoliosis(CS)and to analyse their influencing factors,so as to provide reference for clinical screening and intervention.Methods A to-tal of 149 children with CS were retrospectively collected,and the presence of cardiac anomalies was determined based on the results of transthoracic echocardiography,and the cardiac anomalies were classified into congenital heart disease(CHD)and other cardiac anomalies(OCA)according to the specific features of the anomalies.Basic information and clini-cal characteristics related to CS were collected,and the clinical data of CS patients with and without CHD and CS patients with and without OCA were compared,and binary Logistic regression analysis was used to screen the influencing factors of CS patients with cardiac anomalies.Results Among 149 CS children,a total of 48 cases developed cardiac abnormali-ties,including 10 cases of CHD(atrial septal defect 1,patent foramen ovale 4,patent ductus arteriosus 2,left superior ve-na cava perpetuum 1,dextrocardia 1,and postoperative CHD 1),and 38 cases of OCA[14 cases of mitral regurgitation(mild),34 cases of tricuspid regurgitation(mild),and 4 cases of aortic regurgitation,and 1 case of mitral valve anterior leaflet thickening];the overall incidence of cardiac abnormalities was 32.21%,of which the incidence of CHD was 6.71%and the incidence of OCA was 25.50%.The differences in gender,age,ethnicity,BMI classification,altitude of residence,site of primary curvature,severity of primary curvature,direction of primary curvature,and the ratio of the lon-gitudinal diameter to the transverse diameter of the thoracic cavity were not statistically significant between CS patients with and without CHD,and CS patients with and without OCA(all P>0.05).The results of binary Logistic regression analysis showed that gender,age,ethnicity,BMI classification,altitude of place of residence,site of major curvature,severity of major curvature,direction of major curvature,and the ratio of the longitudinal diameter to the transverse diameter of the thoracic cavity were not influential factors for the cardiac abnormalities in CS children(all P>0.05).Conclusions The incidence of CHD in CS children was 6.71%,with the most common type of patent foramen ovale;the incidence of OCA was 25.50%,with tricuspid regurgitation being the most common.No significant associations were found between gender,age,ethnicity,BMI,altitude of residence,site of primary curvature,severity of primary curvature,direction of primary curvature and the ratio of thoracic longitudinal diameter to transverse diameter and the occurrence of cardiac anomalies in children with CS.
Keywords：congenital scoliosiscardiac anomaliescongenital heart diseaseinfluencing factors
Publication Date：2025-04-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 42-47 )