Application of a hospital-formulated restricted low-residue diet combined with oral polyethylene glycol electrolyte solution in bowel preparation for colonoscopy

LYU Ze; ZHAO Chunhua; HUA Xian; LU Jinnan; WANG Ling; MIN Han

doi:10.3969/j.issn.1002-266X.2025.03.015

Abstract：Objective To evaluate the efficacy of a hospital-formulated restricted low-residue diet combined with oral polyethylene glycol electrolyte solution(PEG)in bowel preparation for colonoscopy and to explore the feasibility of minimizing oral bowel cleanser volume.Methods Totally 120 hospitalized patients scheduled for colonoscopy were ran-domly allocated into three groups(groups A,B,C;with 40 in each),and 39,32,and 36 patients completed the study,respectively.On the day before colonoscopy:patients in the group A received a restricted low-residue diet plus 2 L PEG;patients in the group B received a self-prepared low-residue diet plus 2 L PEG;patients in the group C received a restricted low-residue diet plus 1.5 L PEG.Colonic cleansing efficacy was assessed using the Boston bowel preparation scale(BB-PS),and scores for the right colon,transverse colon,left colon,and the total score were recorded.The adequacy rate of bowel preparation was calculated.At 2 h after the procedure,patients completed questionnaires evaluating subjective expe-riences(abdominal bloating,preparation difficulty,satisfaction).Adverse events were compared among groups.Results Group A exhibited significantly higher BBPS scores in the right colon and total scores as compared with groups B and C(all P<0.05).No significant differences were observed in segmental or total BBPS scores between groups B and C(all P>0.05).The bowel preparation adequacy rates were 89.74%(35/39)in the group A,81.25%(26/32)in the group B,and 86.11%(31/36)in the group C,with no statistically significant differences(all P>0.05).Groups A and B reported higher incidences of abdominal bloating than Group C(all P<0.05).Group B perceived bowel preparation as"ex-tremely cumbersome"more frequently than Groups A and C(all P<0.05).No significant differences were found in adequa-cy rate of bowel preparation or satisfaction scores among these three groups(all P>0.05).Nausea incidence was higher in the groups A and B than in the group C(all P<0.05).Conclusions The hospital-formulated restricted low-residue diet combined with oral PEG achieves effective bowel cleansing with a straightforward protocol for colonoscopy preparation.While reducing the PEG dose alongside standardized dietary regimens maintains acceptable cleansing quality,this ap-proach significantly improves patient tolerability by alleviating abdominal discomfort and reducing nausea incidence.