Clinical characteristics and ultrasound manifestations of different subtypes of breast hamartoma
CHEN Lu
ZHENG Xia
NI Pingjuan
PANG Kunkun
LIU Zhen
ZHANG Feixue
Abstract：Objective To analyze the clinical characteristics and ultrasonic manifestations of different subtypes of breast hamartoma.Methods Fifty-three patients with breast hamartoma were selected and classified into three types based on the content of internal components:mixed type,fat type,and dense type.We retrospectively analyzed the clinical and pathological data,ultrasound findings,and misdiagnosis of three subtypes of breast hamartoma.Results Among the 53 patients with breast hamartoma,there were 34 cases of mixed type,14 cases of fat type,and 5 cases of dense type,all of which were unilateral breast lesions.There were no statistically significant differences in age,disease course distribution,menstrual status,disease symptoms,or disease detection methods among patients with different subtypes of breast hamarto-ma(all P>0.05).Mixed type ultrasound showed mixed echoes,with slightly higher echo masses with blurred edges visible within the low echo masses,presenting a"floating island"sign;fat type ultrasound showed high echogenicity,sometimes slightly low echogenicity,accompanied by linear or small patchy high echogenicity;dense type ultrasound showed uniform low echo with slightly high echo at the edges.The shapes of different subtypes of tumors were mostly regular,presenting as elliptical,with mostly intact capsules,clear boundaries,no calcification,and no significant changes in posterior echoes.The blood flow signals within the masses were not abundant.There were no enlarged lymph nodes in the bilateral axillae.There were statistically significant differences in the longest diameter,relationship between lesion and glandular location,and internal echo among different subtypes of breast hamartoma(all P<0.05),while there were no statistically significant dif-ferences in lesion location,quadrant zoning,morphology,capsule,"ductal"structure,or CDFI(all P>0.05).Among 53 cases of breast hamartoma,20 were misdiagnosed by ultrasound,including 14 cases of lipoma,4 cases of hyperplastic nod-ules,and 2 cases of fibroadenoma;four cases of mixed breast hamartoma were misdiagnosed,including 3 cases of lipoma and 1 case of proliferative nodule;eleven cases of fatty breast hamartoma were misdiagnosed as lipomas;5 cases of dense breast hamartoma were misdiagnosed,including 2 cases of fibroadenoma and 3 cases of proliferative nodules.There was a statisti-cally significant difference in misdiagnosis among different subtypes of breast hamartoma(P<0.05).Conclusions Most cases of breast hamartomas with different subtypes occur unilaterally in the breast,exhibiting minimal differences in clinical features but varying in ultrasound manifestations.Breast hamartomas are prone to misdiagnosis.Mixed type breast hamarto-mas are the least misdiagnosed due to their typical ultrasonic manifestations.However,dense type breast hamartomas most-ly show hypoechoic masses on ultrasound,which is relatively rare and most likely to be misdiagnosed.
Keywords：breast hamartomaultrasound manifestationmisdiagnosis
Publication Date：2025-02-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 95-100 )