Application of CT three-dimensional reconstruction combined with 3D printing technology in liver cancer resection surgery
CHEN Jian
LI Youwei
LIU Yu
LI Miao
LI Feng
ZHOU Luke
YANG Jie
LI Xiaodong
ZHENG Benbo
Abstract：Objective To analyze the application effect of CT three-dimensional reconstruction combined with 3D printing technology in liver cancer resection surgery.Methods Eighty patients with hepatocellular carcinoma were se-lected and divided into the 3D group of 38 cases and conventional group of 42 cases according to different surgical plans.In the 3D group,we used CT three-dimensional reconstruction combined with 3D printing technology for surgical planning and guidance before liver resection surgery,while in the conventional group,we performed liver resection surgery accord-ing to traditional surgical planning,using laparoscopy or laparotomy.We compared the surgical operation time,intraopera-tive blood loss,portal block time,hospital stay,virtual and actual liver resection volume and residual liver volume,the rate of pathologically negative margin,pre-and post-operative liver function[including alanine aminotransferase(ALT),aspartate aminotransferase(AST),total bilirubin(TBIL),and γ-glutamyltransferase(γ-GT)],postoperative complica-tions,as well as tumor recurrence/metastasis rate and survival rate at 1 and 2 years after surgery between two groups.Results The surgical operation time,intraoperative blood loss,and hepatic portal block time in the 3D group were lower than those in the conventional group,and the virtual and actual residual liver volume was higher than that in the conven-tional group(all P<0.05).There was no statistically significant difference in hospitalization time or virtual and actual liver resection volume between the two groups(all P>0.05).The rate of pathologically negative margins in the 3D group was higher than that in the conventional group(P<0.05).The serum levels of ALT,AST,TBIL,and γ-GT in the 3D group were lower than those in the conventional group at 3 and 7 days after surgery(all P<0.05).There was no statistically sig-nificant difference in the incidence of postoperative complications between the two groups(P>0.05).There were no statis-tically significant differences in the tumor recurrence/metastasis rate or survival rate at 1 and 2 years after surgery between the two groups(P>0.05).Conclusion The combination of CT three-dimensional reconstruction and 3D printing tech-nology for liver cancer resection surgery can avoid tumor residue,protect residual liver volume,and reduce liver function damage.
Keywords：computed tomographythree-dimensional reconstruction3D printing technologyliver neoplasmsliver carcinoma
Publication Date：2025-02-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 80-84 )