Relationship between ultrasound left atrial volume index and pericardial fat thickness in patients with HFpEF
WANG Shixin
GUO Liping
LI Dandan
GAO Zhensen
ZHANG Wenwen
MIAO Wei
Abstract：Objective To analyze the relationship between ultrasound left atrial volume index(LAVI)and pericardi-al fat thickness in patients with heart failure with preserved ejection fraction(HFpEF),and to explore the potential predic-tive value of pericardial fat thickness for HFpEF.Methods Seventy-two patients with HFpEF were selected as the HF-pEF group,and 69 healthy individuals without a history of heart failure were selected as the control group.Echocardiogra-phy was performed on the subjects using a colour ultrasound diagnostic instrument,and LAVI was detected using the modi-fied Simpson method.The measurements of epicardial adipose tissue(EAT)thickness on the anterior wall right ventricu-lar,paracardial adipose tissue(PAT)thickness on the anterior wall of right ventricular,and EAT thickness in the left atrioventricular groove were obtained at end-diastole.The receiver operating characteristic(ROC)curves were plotted,and the area under the curve(AUC)was calculated to analyse the predictive efficacy of right ventricular anterior wall EAT thickness,right ventricular anterior wall PAT thickness and left atrioventricular groove EAT thickness on LAVI≥34 mL/m2 in patients with HFpEF;Spearman correlation analysis was employed to examine correlations between the right ventricular anterior wall EAT thickness,right ventricular anterior wall PAT thickness,left atrioventricular EAT thickness and LAVI in HFpEF patients.Results LAVI,right ventricular anterior wall EAT thickness,right ventricular anterior wall PAT thickness and left atrioventricular groove EAT thickness were higher in the HFpEF group than in the control group(all P<0.05).ROC curve analysis showed that the AUC of the right ventricular anterior wall EAT thickness,right ventricular an-terior wall PAT thickness and left atrioventricular groove EAT thickness in the prediction of LAVI≥34 mL/m2 was 0.710,0.508,and 0.684.Spearman correlation analysis showed that the right ventricular anterior wall EAT thickness,left atrioventricular groove EAT thickness were positively correlated with LAVI(r=0.334,0.275,respectively;both P<0.01),and there was no correlation between right ventricular anterior wall PAT thickness and LAVI(r=0.060,P=0.477).Conclusion Ultrasound LAVI in patients with HFpEF was positively correlated with right ventricular anterior wall EAT thickness and left atrioventricular groove EAT thickness,and the correlation between right ventricular anterior wall EAT thickness and LAVI was even higher,which might be one of the relevant indexes to assess HFpEF.
Keywords：pericardial adipose tissueepicardial adipose tissueparacardial adipose tissueleft atrial volume in-dexheart failure with preserved ejection fractionechocardiography
Publication Date：2025-01-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1-5 )