Application of PI and PVI on weaning outcomes in mechanically ventilated patients
WU Xiaoxia
YUE Weigang
YAN Boling
LI Bin
Abstract：Objective To observe the application effect of pulse perfusion index(PI)and pleth variability index(PVI)on weaning outcomes in mechanically ventilated patients.Methods Totally 116 mechanically ventilated patients who prepared to weaning were selected.Spontaneous breathing test(SBT)was performed with T-tube mode after weaning screening.If the patients'spontaneous breathing time exceeded 48 hours after extubation,it was considered as successful weaning.The patients were divided into the successful weaning group(90 cases)and the failure weaning group(26 cases)according to the weaning outcomes.PI and PVI of the patients before and after SBT were monitored by pulse oximeter Radi-cal-7,and the changes of PI and PVI before and after SBT were also calculated(ΔPI,ΔPVI).ROC curves were used to evaluate the predictive value of PI,PVI before SBT,and ΔPI,ΔPVI on the weaning outcomes of mechanical ventilation pa-tients.Results Compared with the failure weaning group,PVI before SBT,PI after SBT,PVI after SBT,ΔPI,ΔPVI af-ter SBT increased in the successful weaning group(all P＜0.05).When the PVI before SBT was greater than 14.0%,its sensitivity in predicting successful weaning in mechanically ventilated patients was 86.1%,specificity was 79.2%,AUC was 0.860,and 95%CI was 0.766-0.953.When ΔPVI was greater than 10.5%,its sensitivity in predicting successful weaning in mechanically ventilated patients was 91.7%,specificity was 83.3%,AUC was 0.905,and 95%CI was 0.831-0.978.When ΔPI was greater than 12.5%,its sensitivity in predicting successful weaning in mechanically ventilated pa-tients was 88.9%,specificity was 80.8%,AUC was 0.936,and 95%CI was 0.877-0.996.Conclusions PI before SBT can not predict the weaning outcome of mechanical ventilation patients effectively,but PVI before SBT and ΔPI and ΔPVI have good predictive value for weaning outcome of mechanical ventilation patients.
Keywords：pulse perfusion indexpleth variability indexmechanical ventilationweaning
Publication Date：2023-12-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 41-44 )