Application value of quantitative CT in the apical segmental and the sub-segmental bronchi of right upper lobe for evaluating the condition of chronic obstructive pulmonary disease
YANG Fei
JI Mengmeng
ZHU Xiaolong
WANG Dawei
ZOU Dianjun
WANG Xiaocan
CUI Shujun
Abstract：Objective To evaluate the application value of quantitative CT in the apical segmental and sub -segmental bronchi of right upper lobe for assessment of acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods Thirty-one cases of COPD patients in acute exacerbation period and remission period with complete clinical data were selected.The airway wall thickness(WT),airway diameter ratio(TDR),airway wall area(WA)and the percentage of airway wall area accounting for the total cross-sectional area(WA%)of the apical segmental and sub-segmental bronchi of the right upper lobe were measured and calculated by multi-slice spiral CT(MSCT)on the same COPD patient in acute exacerbation period and remission period.The relationship between the four parameters and pulmonary function indexes (FEV1%and FEV1/FVC)was analyzed.Results TDR of the apical segmental bronchi of right upper lobe in the COPD patients in the acute exacerbation period was greater than that in the remission period(P<0.05), and WT,TDR, WA, WA%of the sub-segmental bronchi of the right upper lobe were greater than those in the remission period(P<0.05 or P<0.01).There was no correlation between WA %,WA,TDR,WT and FEV1%,FEV1/FVC in the apical segmental bron-chi of right upper lobe of patients in the acute exacerbation period and remission period(all P>0.05).In the sub-segmental bronchi of right upper lobe of patients,WA%was negatively correlated with FEV 1%(r=-0.425, -0.400,P<0.05), and TDR was negatively correlated with FEV 1%(r=-0.517, -0.473, both P<0.05).Conclusion Quantitative CT shows that the stenosis and wall thickening degree in the sub-segmental bronchi of right upper lobe are significantly higher than those in apical segmental bronchi of COPD patients in acute exacerbation period,and quantitative CT measurement could be helpful to identify COPD patients with acute exacerbation.
Keywords：chronic obstructive pulmonary diseaseacute exacerbationmulti-slice spiral CTquantitative parame-terapical segmental bronchus of right upper lobe
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 14-17 )