Role of Gd-EOB-DTPA-enhanced MRI in assessing the risk of liver failure after major liver resection
YU Qianjun
CHENG Long
ZHU Yongqiang
DU Feizhou
HUANG Min
WANG Tao
Abstract：Objective To investigate the role of Gd-EOB-DTPA-enhanced MRI in assessing the risk of liver failure after major liver resection.Methods Thirty-six patients with three or more segments of the liver partial resection were enrolled.All patients underwent Gd-EOB-DTPA-enhanced MRI,liver-enhanced CT,ICG clearance test,Child-Pugh score,and liver function serum test for preoperative checkup.The relationships of preoperative liver function,remnent hepatocellular uptake index (rHUI),standard remnant hepatocellular uptake index (SrHUI) and intraoperative relevant indicators with postoperative liver failure risk were analyzed.We used the receiver operating characteristic curve (ROC) to evaluate the diagnostic value of rHUI and SrHUI in predicting the risk of liver failure.Results Eight patients (22.22％) experienced the risk of hepatic failure.There were significant differences in the rHUI,SrHUI,and albumin of patients with the risk of liver failure and without the risk (all P ＜ 0.05).The ROC area under the curve (AUC) of rHUI and SrHUI was 0.835 and 0.864,respectively (sensitivity:71.4％ and 85.7％,specificity:87.5％ and 75.0％,cut-off value:0.614 and 0.344,95％ confidence interval:0.654-0.947 and 0.730-0.998).Conclusion Gd-EOB-DTPA-enhanced MRI can accurately assess the residual liver function,and has important significance in assessing the risk of liver failure after major liver resection.
Keywords：liver neoplasmshepatic failureGd-EOB-DTPA-enhanced MRIhepatectomy
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 5-8 )