Effects of hs-CRP and VEGF on major adverse cardiovascular events in patients with acute myocardial infarction after percutaneous coronary intervention
AI Min
YAN Changfu
XIA Fuchun
ZHOU Shuanglu
HE Jian
Abstract：Objective To explore effects of serum high-sensitivity C-reactive protein ( hs-CRP) and vascular endo-thelial growth factor (VEGF) on the major adverse cardiovascular events (MACE) in patients with acute myocardial infarc-tion (AMI) after percutaneous coronary intervention (PCI).Methods Totally 116 patients with AMI were treated by PCI.According to the occurrence of MACE after PCI , the patients were divided into the MACE group of 20 cases and non-MACE (NMACE) group of 96 cases.We analyzed the levels of hs-CRP and VEGF in patients before PCI , and at 1 h, 24 h, and 7 d after PCI.Results At 1 h, 24 h, and 7 d after PCI, the serum hs-CRP levels were (5.79 ±1.13), (6.87 ± 1.42), and (3.51 ±0.89) mg/L in the MACE group, and the serum VEGF levels were (167.8 ±49.8), (146.8 ± 43.9), and (121.5 ±29.6) pg/mL, respectively;the serum levels of hs-CRP in the NMACE group were (4.57 ±1.09), (5.38 ±1.21), and (2.67 ±0.58) mg/L, and the serum hs-CRP levels were (145.7 ±40.3), (115.6 ±39.7), and (95.7 ±21.7) pg/mL, respectively.Significant differences were found at different time points between these two groups (all P<0.05).Conclusion The serum hs-CRP and VEGF levels have some clinical value in predicting the occurrence of MACE in patients with AMI after PCI .
Keywords：acute myocardial infarctionpercutaneous coronary interventionhigh-sensitivity C-reactive proteinvas-cular endothelial growth factor
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 16-18 )