Effects of different body mass index in diabetes patients on incidence of hypertension
HUANG Yuyan
SUN Jing
CHEN Xiuqing
TIAN Jian
LIU Xiaocui
CHEN Shuohua
LIU Peng
WU Shouling
Abstract：Objective To explore the relationship between body mass index (BMI)and the new-onset hypertension in diabetic patients.Methods According to the baseline BMI measurement from June 2006 to October 2007,2 367 diabetic patients were divided into the obese group (BMI <28 kg/m2 )and non-obese group (BMI≥28 kg/m2 ),and in accordance with the baseline BMI quartile,they were divided into groups with BMI <23,23-<25,25-<27 and ≥27 kg/m2 .During June 2008 to October 2009,a repeated health examination was carried out to observe the incidence of hypertension in dia-betic patients with different BMI.Multiple Logistic regression analysis was used to test the BMI level and the hypertension. Results ① The incidence rate of hypertension was 38.36% in 2 367 diabetic patients,and the incidence rate in males (40.21%)was higher than that in females (31.03%),(P <0.05).The incidence of hypertension was higher in the obese group (48.91%)than that (35.83%)in the non-obese group(P <0.01).The incidence rates of hypertension in patients with BMI <23,23-<25,25-<27 and ≥27 kg/m2 were 29.83%,36.15%,40.81% and 46.62%,respective-ly,and significant difference was found between them (P <0.01).After the stratification by gender,the incidence rates of hypertension in males were 32.06%,37.45%,43.51% and 47.63%,respectively (P <0.01).The incidence rates of hypertension in females were 22.92%,28.89%,29.57% and 42.97%,respectively (P <0.01).② Univariate analysis showed that the overall risk of hypertension odds ratio (OR)was 1.332,1.622 and 2.055 in patients with BMI 23-<25, 25-<27 and ≥27 kg/m2 as compared with that with BMI <23 kg/m2 .The OR value was 2.534 for females with BMI≥27 kg/m2 ,and 1.632 and 1.927 for males with BMI of 25-27 and ≥27 kg/m2 ,respectively.Multivariate Logistic regression analysis showed that after adjustment for age,systolic blood pressure and other factors,the OR for all and males with BMI of 25-27 kg/m2 were 1.400,1.412,the OR values for all,males and females with BMI≥27 kg/m2 were 1.729,1.596, and 2.636 as compared with those of the patients with BMI <23 kg/m2 .Conclusion BMI may be an risk factor for the new-onset hypertension in diabetic patients,and BMI has a greater impact on the incidence of hypertension in male diabetic patients .
Keywords：diabetes mellitusbody mass indexhypertension
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 25-28 )