Assessment of different obesity indexes on risk of coronary artery disease, hypertension and/or diabetes mellitus

FAN Yongwang; MA Jun; QIU Jian; HUANG Jiangming; HUANG Xiaomin; XU Yehao; XU Lin

doi:10.3969/j.issn.1002-266X.2017.01.004

Abstract：Objective To observe the differences of obesity in patients with coronary artery disease (CAD),hyper-tension and /or diabetes mellitus,and to investigate the assessment of different obesity indexes on risk of these illnesses. Methods A total of 643 patients with or without CAD and /or hypertension with/without diabetes were recruited in our study.According to the specific diseases,patients were divided into five groups:the CAD group (120 cases with CAD), the hypertension group (127 cases with hypertension),CAD combined with hypertension group (108 cases),the CAD and /or hypertension combined with diabetes group (164 cases,short for combined diabetes group),and the control group (124 cases without the above related diseases).Analysis of variance was used to compare the differences in the body mass index (BMI),abdominal circumference (WC),and waist index (WHtR)among the 5 groups.Binary logistics regression was used to assess the risk of illness,and receiver operator characteristics (ROC)analysis was used to assess the ability of diagnosis.Results There were significant differences in BMI,WC and WHtR among the five groups (all P <0.05).Lo-gistic regression analysis showed that BMI,WC and WHtR were independent risk factors for hypertension and CAD com-bined with hypertension.WC was an independent risk factor for the combined diabetes mellitus.ROC curve analysis showed that the single obesity index for the diagnosis of disease was weak,but when combined with a number of indicators, it could improve the diagnostic efficiency.Conclusions The degree of obesity in patients with CAD,hypertension and /or diabetes is higher than that of patients without the above disease.Different obesity indexes play different roles in assessment of the degree of obesity and the risk of illness.Separately application of obesity index is an initial screening tool for illness.