Value of echocardiographic Tei index in evaluating fetal cardiac function of pregnant women with gestational diabetes mellitus
KAN Quan′e
LU Ping
LU Yu
YU Lu
LI Quanzhong
Abstract：Objective To investigate the changes of fetal cardiac function and the function of echocardiographic Tei index in evaluation of fetal cardiac function of pregnant women with gestational diabetes mellitus (GDM).Methods To-tally 108 cases of pregnant women with GDM were divided into the well-controlled group (GDM1 group,56 cases)and poorly-controlled group (GDM2 group,52 cases)according to their blood glucose levels.Meanwhile,we selected 50 cases of age,gestational age and BMI-matched normal pregnant women as the controls (control group).The fasting plasma glu-cose (FPG),postprandial glucose (2 h PG)and glycosylated hemoglobin (HbA1c )were measured in these three groups. The fetal cardiac structure,left and right ventricular Tei indexes in each group were measured by Doppler echocardio-graphy.Results FPG,2 h PG and HbA1c of the GDM2 group were higher than those of the GDM1 group and control group (all P <0.05).The fetal left ventricular wall thickness (LVWT),right ventricular wall thickness (RVWT),right ven-tricular end-diastolic diameter (RVDd),left ventricular fractional shortening (LVFS),right ventricular fractional shorten-ing (RVFS)and left ventricular ejection fraction (LVEF)of GDM2 group were significantly higher than those of the control group (all P <0.05).The fetal RVDd,right ventricular end-systolic diameter,LVFS and LVEF of the GDM2 group were higher than those of the GDM1 group (all P <0.05).The GDM1 group's fetal LVFS was higher than that of the control group (P <0.05).The Tei index of fetal left and right ventricular of GDM2 group and GDM1 group was significantly higher than that of the control group,and the difference was statistically significant (all P <0.05).The average Tei index of fetal left and right ventricular of GDM2 group was higher than that of the GDM1 group and control group (all P <0.05).Con-clusions Tei index,which is associated with fetal cardiac function in GDMpregnant women,can be used as a simple and reliable indicator in the clinical comprehensive evaluation of fetal cardiac involvement.
Keywords：gestational diabetes mellitusechocardiographyTei indexblood glucose controlfetal cardiac function
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 7-10 )