Imaging diagnosis of cerebraI parenchyma ependymoma

MA Ling; WU Jingwen; YU Hao; WANG Xianlong; WEN Zhibo

doi:10.3969/j.issn.1002-266X.2016.43.003

Abstract：Objective To investigate the features of X-ray computed tomography (CT)and magnetic resonance ima-ging (MRI)of cerebral parenchyma ependymoma.Methods Twenty-five patients with cerebral parenchyma ependymoma which were confirmed by pathological examination after surgical resection,including 11 ependymomas and 14 anaplastic ependymomas were selected.The CT and MRI features of these patients were analyzed.Results The lesion locations of 24 cases were closely related to adjacent ventricles which were compressive deformation,and 1 case was not,it located in the left parietal-occipital lobe.Fourteen patients underwent CT scan,heterogeneous mass was found in 8 cases,and peritu-moral calcification or intratumoral calcification were found in 6 cases.In the 20 patients after MRI,the solid part of the tumors showed hypointense on T1 WI,isointense or slight hyperintense on T2 WI,13 of which showed cystic degeneration in periphery regions of the lesions.And the intracapsular part showed slight hyperintense on Flair.There was remarkable en-hancement in the solid part and the peripheral cystic wall.Decreased NAA and increased Cho and Lip were found in 9 ca-ses who underwent magnetic resonance spectrum (MRS).Three cases of anaplastic ependymomas performed amide proton transfer (APT)imaging,the APT rate was 2.96,3.76 and 3.48,respectively.Conclusions Cerebral parenchyma ependymoma has some characteristic imaging features,such as,a heterogeneous intensity tumor with central necrosis,cal-cification and peripheral cystic change,decreased NAA peak and increased Cho and Lip peak on MRS.Meanwhile,the in-creased APT of tumor core could help to predict the tumor grade.