Comparison of therapeutic dose and efficacy between single arc and double arc stereotactic body radiotherapy for early lung cancer patients
ZHANG Jiyong
HONG Danli
WU Lili
LU Jiayang
Abstract：Objective To compare the therapeutic dose and efficacy between the single arc and double arc stereotac-tic body radiotherapy plans for early lung cancer patients with flattening filter free patterns.Methods Eighteen patients with lung cancer of the early stage were selected in this study,and each patient was arranged single arc stereotactic body ra-diotherapy (S-RA)and double arc stereotactic body radiotherapy (D-RA)plans using the Eclipse 10.0 treatment planning system with 6 MV flattening filter-free (FFF)photon beams.The prescription dose was 48 Gy,12 Gy/time and for 4 times.Comparisons between D-RA and S-RA plans in the target volume received 95%prescription dose (V95%),the tar-get volume received 90%prescription dose (V90%),the target volume received 105%prescription dose (V105%),con-formity index (CI),homogeneity index (HI),organs at risk (OARs)doses,planning time (PT),monitor units (MU) and treatment time (TT)were conducted.Results No significant difference was found in V90%,V95%,and V105%;in PT and MU between D-RA and S-RA,all P>0.05.Significant difference was found in CI and TT between D-RA and S-RA,all P<0.05.For the OAR,there was no significant difference between the D-RA and S-RA,P>0.05.Conclusions D-RA and S-RA provids a superior PTV coverage,and all OAR dose meets the constraint level of RTOG 0915 protocol. S-RA shows no significantly difference in PTV coverage and OAR as compared with D-RA.The CI and HI of D-RA are bet-ter than those of S-RA.S-RA shows shorter treatment time and less MU number as compared with D-SA.
Keywords：single arc stereotactic body radiotherapydouble arc stereotactic body radiotherapyflattening filter free patternslung carcinomalung neoplasms
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 47-49 )