Clinical efficacy of Huashi Xingyu Qingre decoction in treatment of OLP and its effects on content of ALB and sIgA in saliva of OLP patients
XU Yanzhi
ZHANG Yangyang
LIU Jian
LIU Tiejun
ZHANG Meiji
Abstract：Objective To evaluate the clinical efficacy of Huashi Xingyu Qingre decoction (HXQD) in treatment of oral lichen planus ( OLP) , and to analyze the effects of HXQD on the content of OLP patients'ALB and secretory IgA ( sI-gA) in saliva.Methods Thirty cases of OLP patients ( observation group) were treated by HXQD, 200 mL, once respec-tively each morning and evening, agent 1/d, and for 8 weeks.Meanwhile, 30 healthy people were selected as the control group.The saliva samples of OLP patients and healthy people were collected to detect serum albumin and sIgA in saliva be-fore and after treatment.Results After treatment, 16 cases were significantly effective, 11 cases were effective, 3 cases were invalid in the observation group, and the total effective rate was 90%(27/30).OLP The level of ALB in saliva was higher and sIgA was lower in observation group than that of the control group before treatment (all P<0.05).Compared with before treatment, the content of ALB was decreased after treatment, while the level of sIgA was increased, and the differences were statistically significant (all P<0.05).Conclusions HXQD has significant clinical effect on OLP, and it can reduce ALB and increase sIgA in OLP patients'saliva.
Keywords：Huashi Xingyu Qingre decoctionoral lichen planusalbuminsecretory IgA
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 98-100 )