ToxicoIogicaI studies on preparations of chito-oIigosaccharide and E jiao
ZHOU Xiaolin
LU Lianhua
GUO Jie
XIE Wei
YAN Yan
CHENG Dong
YANG Fei
YAO Wenhuan
Abstract：Objective To study the toxicity of chito-oligosaccharide and E jiao preparations.Methods The acute toxicity test of mice was used to detect the acute toxicity of chito-oligosaccharide and E jiao preparations;Ames test,bone marrow cell micronucleus test and sperm shape abnormality test of mice were performed for the genetic toxicity;and the 30-day feeding test of mice was used to detect the subacute toxicity.Results The acute toxicity test of Chito-oligosaccharide and E jiao preparations showed they were non-toxic.The results of genetic toxicity test were all negative,including Ames test,micronucleus test and sperm shape abnormality test.The results of 30-day feeding test had no toxic effect on the ob-served indexes of rats.Conclusion Chito-oligosaccharide and E jiao preparations are non-toxic substances and have no acute toxicity,genetic toxicity and subacute toxicity.
Keywords：chito-oligosaccharideE jiaoacute toxicity testgenetic toxicity testsubacute toxicity testrats
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 24-27 )