Association between metabolic syndrome and the count of lymphocyte in male and female Beijing adults’population
Abstract：Objective To explore the association between the count of lymphocyte and the occurrence of metabolic syndrome (Mets)in a cohort study in male and female Beijing adults specifically in gender.Methods Clinical data of 7 489 cases who took at least 3 health examination from 1st January 2007 to 31th December 2012 were retrospectively ana-lyzed in Beijing Electric Power Hospital and Beijing Xiaotangshan Hospital.The count of lymphocyte of research objects was obtained from the blood routine examination.And the lymphocytes were divided into 4 levels according to the quartile (Q1≤25%,Q2:25%-50%,Q3:50%-75%,Q4>75%)in gender.Metabolic syndrome was diagnosed by the last data of health examination.Generalized estimating equation model was used to assess the relationship between metabolic syndrome and the lymphocyte.Results During the 5 years’follow-up,378 cases appeared MetS,including 203 males and 175 fe-males.And the incidence density of Mets was 12.67 per 1000 person-years.Compared with Q1,the males’BMI increased in Q4 (RR=2.200 8,95% CI:1.090 8-2.045 7 ),and the males’TG increased in Q1,Q2 and Q3(RR=1.208 4, 1.442 5,1.707 7,95%CI:1.032 3-1.414 6,1.210 3-1.7192,1.406 5-2.073 5).Compared with Q1,the females whose lymphocytes were Q4 increased the risk of MetS (RR=2.200 8,95%CI:1.221 9-3.964 0).Conclusions The increase of males’lymphocytes may associate with the increase of BMI and TG,and the increase of females’lymphocytes may associ-ate with the occurrence of MetS in Beijing adults.
Keywords：metabolic syndromelymphocytegendercohort studiesgeneralized estimating equationsBeijing
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 14-17 )