Evaluation of the effect of bedside rapid detection of N-terminal pro-brain natriuretic peptide on cardiac functions of patients with gestational hypertension
TIAN Hui
WU Tie-jun
ZHANG Lu-jun
CUI Yu-jing
QU Ai-jun
TIAN Suo-chen
Zou Xiu-li
Abstract：Objective To observe the changes in levels of venous blood N-terminal pro-brain natriuretic peptide ( NT-proBNP) of patients with gestational hypertension, and to explore the diagnostic values of bedside rapid detection of NT-proB-NP.Methods We selected 69 patients with gestational hypertension, including the gestational hypertension group (n=16), the preeclampsia group (n=30) and the eclampsia group (n=23) and another 30 age-matched cases of normal pregnancy women.Within 24 hours after their entering to the ICU, the acute physiology and chronic health evaluation ( APACHE II) scores were evaluated;the systolic pressure, the diastolic pressure, the oxygenation index and LVEF were recorded.On the first, the third and the fifth day of their entering to the ICU, bedside rapid detection technololy was used to detect the NT-proBNP in venous blood to analyze the changes of NT-proBNP in each group and the severity of the lesion.Results There were statistical differences in the APACHE II scores, the systolic pressure, the diastolic pressure, the oxygenation index and LVEF among thees three groups (all P<0.01).On the first day of their entering the ICU, the NT-proBNP level of the ec-lampsia group was higher than those of the preeclampsia group and the gestational hypertension group (all P<0.05).After the treatment, the level of NT-proBNP of each group was decreased, and there was statistically significant different in the re-sult on the fifth day as compared with that of the first day (all P<0.05).The APACHEⅡscore on the first day of entering ICU for the gestational hypertension group was positively correlated with the NT-proBNP level (r=0.752, P<0.01).Con-clusion Bedside rapid detection of NT-proBNP is of great importance for the diagnosis of gestational hypertension.
Keywords：hypertensive disorder complicating pregnancyN-terminal pro-brain natriuretic peptidebedside detec-tion technologyacute physiology and chronic health evaluation
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 7-9 )