Changes in levels of thyroid hormone of PCOS about luf of follicle during ovulation induction and the significance
WANG Yan-li
LIU Ping
Abstract：Objective To observe the changes in levels of thyroid hormone in patients with polycystic ovary syndrome ( PCOS) about luf of follicle during ovulation induction and to investigate the significance.Methods Eighty-nine patients with PCOS were induced ovulation by CC+HCG.During menstrual cycle of induced ovulation, when the follicles grew to 18-20 mm and can be normally educed, we took these as the control group (49 cases) , and the other follicles failed to dis-charge, we took those as the luf group (40 cases).The levels of thyroid hormone at different follicular development period were detected.Results The levels of thyroid hormone were not significantly different when the diameter of follicles grew to 5 mm, 10 mm and 15 mm during the follicular phase.When the follicles grew to 20mm size, the levels of T3 , T4 and TSH of luf follicle were respectively (1.97 ±0.17) nmol/L, (97.43 ±0.16) nmol/L and (3.43 ±0.10) uIU/mL in the luf group;They were (2.69 ±0.15) nmol/L, (124.38 ±0.29) nmol/L and (1.38 ±0.18) uIU/mL in the control group, and significant differences were found in the levels of T3 , T4 and TSH ( all P<0.05) .Conclusion The levels of serum T3 and T4 in patients with PCOS about luf of follicle during the ovulation induction are decreased and TSH is in-creased, and the changes in levels of thyroid hormone may be related with the dysfunction of ovulation induction.
Keywords：polycystic ovary syndromeinfertilityassisted reproductive techniquelufthyroid hormone
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 34-35 )