Effects of low-dose of phenylephrine in prevention of hypotension after combined spinal-epidural anesthesia in cesarean patients
LU Yu-qing
LI Xin
YANG Yuan-dong
FENG Yang-yang
ZHANG Xiang-dong
Abstract：Objective To observe the clinical effects of low-dose of phenylephrine in prevention of hypotension after combined spinal-epidural anesthesia ( CSEA) in cesarean patients .Methods Sixty cases of cesarean patients ( ASA I-Ⅱ) were randomly divided into two groups with 30 cases in each group: phenylephrine group ( group A ) and control group (group B).After the CSEA, patients in the two groups all received the liquid coload .For group A, phenylephrine was in-jected within 15 min.The changes of mean arterial pressure ( MAP) and heart rate ( HR) in the two groups were observed and compared before and after anesthesia .At the same time, complications, such as fidget, shiver and vomiting were also recorded.Newborns 1 min and 5min Apgar scores were estimated.Results MAPs in the group A, and HR of the two groups before and after anesthesia were stable (all P>0.05), while MAP was reduced in the group B 10 min after anesthe-sia (P<0.05).The incidence of hypotension was significantly lower , and neonatal 1 min Asgar scores were higher in group A than those of group B (all P<0.05).However, there were no differences in the time from intrathecal injection of medicine to fetal childbirth , operation time, intraoperative infusion and neonatal 5 min Apgar scores between two groups (all P>0.05).Conclusion Low-dose of phenylephrine could effectively prevent hypotension of cesarean patients after CSEA and has a few obvious adverse reactions .
Keywords：combined spinal-epidural anesthesiacoloadphenylephrinehypotensioncesarean
Publication Date：2015-04-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 38-40 )