Predictive value of preoperative neutrophil-lymphocyte ratio on recurrence-free survival in patients with papillary thyroid carcinoma
MA Heng
WANG Xiao-lei
Abstract：Objective To investigate the predictive value of preoperative neutrophil-lymphocyte ratio ( NLR) on re-currence-free survival in patients with papillary thyroid carcinoma ( PTC) .Methods A retrospective study was performed to analyze the clinical data of 135 cases of PTC patients who accepted surgery treatment firstly in Cancer Hospital Chinese Academy of Medical Sciences , from Jan.1999 to Dec.1999.The postoperative follow-up was performed to record the recur-rence-free survival situation until December 2014.A retrospective analysis was used in these cases to calculate the preoper-ative NLR and to study its predicting value .Results The follow-up duration ranged from 6-180 months ( mean 166 months).There were 101 cases of recurrence-free survival in these 135 cases.The peripheral venous blood NLR of the pa-tients was 1.20-4.25.When NLR=2.93, it had the biggest Youden′s index, so we chose NLR =3 as the cut-off point. Multivariate analysis showed that TNM staging and NLR were the independent risk factors for postoperative recurrence -free survival in PTC patients (all P<0.05).Conclusions Preoperative NLR has the predictive value on recurrence-free sur-vival in PTC patients .Preoperative NLR≥3 predicts poorer prognosis of PTC patients .
Keywords：papillary thyroid carcinomaneutrophil-lymphocyte ratiorecurrence-free survival
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 15-17 )