Changes of red blood cell distribution width, hs-CRP and left atria diameter in patients with varying degrees of atrial fibrillation
CAO Wen-zhai
ZHANG Ting
ZHONG De-chao
SHI Zhao-yun
YU Jiang-heng
Abstract：Objective To observe the changes of red blood cell distribution width ( RDW) , high-sensitivity C-reactive protein (hs-CRP) and left atrial diameter in patients with varying degrees of atrial fibrillation (AF), and to investigate their relationship with disease severity.Methods Our study enrolled 111 patients with AF ( AF group) , including 20 ca-ses of paroxysmal AF, 40 cases of persistent AF and 51 cases of permanent AF.Another 109 subjects without AF history were selected as controls ( control group) who matched for sex, age and atherosclerotic risk factors.RWD was detected by automatic blood cell analyzer, ELISA was used to detect the plasma hs-CRP, and echocardiography was used to measure the left atrium diameter.Results The levels of RDW, hs-CRP and left atrial diameter in the AF and control groups were 12.80%±0.91%, (2.50 ±0.62) ng/L, (37.92 ±6.38)mm and 12.22%±0.26%, (1.07 ±0.58) ng/L, (33.65 ± 4.70) mm, respectively;and statistical difference was found (all P<0.05).Furthermore, RDW, hs-CRP and left atrial diameter were increased with the severity of AF types in subgroup analysis (all P<0.05).Conclusion The levels of RDW, hs-CRP and left atrial diameter of AF patients increase, which is related with the AF severity.
Keywords：atrial fibrillationred blood cell distribution widthhigh-sensitivity C-reactive proteinleft atrial diameter
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 8-10 )