CorreIation anaIysis of carotid artery eIasticity and serum adhesion moIecuIe in sugar reguIation damaged patients
WANG Xiao-mei
JIN Tao
WANG Xia
FEI Da-dong
ZHOU Jing
Abstract：Objective To observe the correlation of carotid artery elasticity and serum adhesion molecule in sugar reg -ulation damaged patients .Methods In all subjects , the intima-media thickness ( IMT) of carotid arteries was measured with high resolution ultrasound.The pressure-strain elastic modulus (Ep), stiffness parameter(β), arterial compliance ( AC) and pulse wave velocity ( PWVβ) were detected by ultrasonic vascular echo tracking technology ( ET) .Blood Pres-sure, body mass index, blood glucose, lipids, insulin resistance index, VCAM-1, ICAM-1 were tested.Results Com-pared with NGT group, Ep,βand PWVβin IGR were significantly higher (all P<0.05), but AC did not change obvious-ly(P<0.05).Compared with NGT group, VCAM-1, ICAM-1 in IGR group were increased significantly (all P<0.05). By correlation analysis, VCAM-1, ICAM-1 in IGR group were positively correlated with Ep,βand PWVβ(all P<0.05), and negatively correlated with AC (all P<0.05).Conclusion There have been changes of carotid artery elasticity and endothelial function disorder in the sugar regulation damaged patients .Comprehensive interventions should be carried out in IGR patients as soon as possible .
Keywords：impaired glucose regulationcarotid atherosclerosiselasticity of blood vesselsadhesion molecule
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 20-22 )