The distribution and drug resistance change of pathogenic bacteria of steriIe body fIuids from cancer patients
BAI Chang-sen
LI Ding
ZHANG Qing
ZHANG Wen-fang
ZHENG Shan
ZHANG Peng
Abstract：Objective To explore the distribution and drug resistance of pathogens isolated from sterile fluid of cancer patients of a hospital during the period of 2010-2012 .Methods VITEK 2-Compact automatic analysis system was used for identification and susceptibility of bacteria and fungi .Whonet5.6 was used for statistic.Results Total of 3 323 strains were identified during the period of 2010-2012 , and most of them were isolated from puncture fluid , blood, bile, etc, ac-counting for 93.7%.Sterile body fluids infection was more common in the Stomach , Hepatobiliary and Colorectal Cancer department, accounting for 51.7%.The ratio of Gram-negative bacteria, Gram-positive bacteria and fungi were 48.8%, 45.6%, 5.6%, respectively.Gram-positive bacteria showed high sensitive to Vancomycin , Linezolid and Tigecycline. Gram-negative bacteria exhibited high sensibility to Carbapenems , Amikacin and Piperacillin /Tazobactam .Drug resist-ance of Yeasts to commonly used antifungal was low .Conclusion Pathogens isolated from sterile body fluids of cancer pa-tients was complex , and the resistant rate to various antibiotics do not change significantly .
Keywords：cancersterile body fluidspathogenic bacteriadrug resistance change
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 5-8 )