Analysis of etiology and risk factors for watershed cerebral infarction
QIU Shi
WANG Qi
ZHAO Jing
LUO Bin
LI Ji-lai
DU Ji-chen
Abstract：Objective To investigate the etiology and risk factors for watershed cerebral infarction ( WSI) and to pro-vide the theoretical basis for the prevention and treatment.Methods Eighty-six patients with WSI were recruited from Oc-tober 2012 to May 2014 in department of neurology of Aerospace Center Hospital, over the same period selected age and sex matched 86 non-WSI persons as control group.Clinical and demographic features and neuroradiological features were com-pared between two groups.Results Compared with the non-WSI group, WSI group had a higher incidence of diabetes mellitus and hpoperfusion events (P=0.024 and P=0.043, respectively).However, WSI group had lower levels of aver-age systolic blood pressure and mean arterial blood pressure than non-WSI group ( P=0.016 and P=0.030, respective-ly) .WSI group had a higher rates of small cortical infarcts, moderate to severe stenosis or occlusion in the middle cerebral artery and internal carotid, and no displaying of anterior and posterior communicating artery than non-WSI group ( P=0.000, 0.016, 0.007, 0.021, respectively).The openness rate of both anterior and posterior communicating artery in WSI group is lower than that in non-WSI group (P=0.033).Conclusions Hemodynamic compromise caused by moder-ate to severe stenosis or occlusion of cerebral arteries or hypoperfusion, microembolization and the colleteral ability of Willis circle may be all involved in the occurrence of WSI.
Keywords：watershed cerebral infarctionhemodynamic compromisemicroembolicWillis circlepathogenesis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 19-21 )