Efficacy of postoperative patient-controlled intravenous analgesia in smoking patients undergoing thoracic surgery

CAI Xing-zhi; YU Ai-lan; ZHANG Zong-wang; LIU Dong-hua; ZHANG Ping

doi:10.3969/j.issn.1002-266X.2014.31.019

Abstract：Objective To investigate the effect of postoperative patient-controlled intravenous analgesia ( PCIA ) in smoking patients undergoing thoracic surgery .Methods The retrospective analysis method was used .Totally 152 male pa-tients undergoing thoracic surgery and received postoperative PCIA were divided into the non -smoking group ( group NS , n=70) and smoking group (group S, n=82).The dosage of sufentanil during surgery , operation time, cumulative amount of self-administered sufentanil at 24 and 48 h after surgery were compared between the two groups .The numerical rating scale ( NRS) was used to assess the tranquillization and coughing pain intensity during 0-48 h after surgery .Analgesia re-lated adverse reactions were observed .Results There were no significant differences in the dosage of sufentanil during surgery and operation time between groups NS and N (all P>0.05).The cumulative amount and dosage per body weight of sufentanil at 24 and 48 h in the group S were significantly higher than that in the group NS , and the NRS scores at tran-quillization and coughing (0-48 h after surgery) were significantly higher in the group S than those of the group NS (all P<0.05).No significant differences were found in the postoperative complications such as nausea and vomiting , sedation, and the incidence of respiratory depression between the two groups (all P>0.05).Conclusion Compared with non-smokers, smokers have more severe postoperative pain and require a higher dosage of PCIA used medicine , but there are no significant differences in PCIA-related adverse reactions .